SMART: stroke-like migraine attacks after radiation therapy

Authors: Black, DF; Bartleson, JD; Bell, ML; Lachance, DH

Source: Cephalalgia, Volume 26, Number 9, September 2006 , pp. 1137-1142(6)

Publisher: Blackwell Publishing

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Abstract:

Black DF, Bartleson JD, Bell ML & Lachance DH. SMART: stroke-like migraine attacks after radiation therapy. Cephalalgia 2006; 26:1137-1142. London. ISSN 0333-1024

We describe two adults with stroke-like migraine attacks after radiation therapy (SMART syndrome), propose revised diagnostic criteria, and review the previously reported patients. `SMART' is an acronym for a newly recognized syndrome which occurs as a delayed consequence of cerebral irradiation and consists of prolonged, unilateral, migrainous neurological symptoms with transient, dramatic cortical gadolinium enhancement of the affected cerebral hemisphere and is sometimes punctuated by generalized seizures and ipsilateral EEG slowing. Although the neurological symptoms can last for weeks, full recovery occurs. An appropriate evaluation should exclude alternative explanations.

Keywords: Migraine; MRI brain scan; radiation therapy; seizure; stroke

Document Type: Research article

DOI: 10.1111/j.1468-2982.2006.01184.x

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