@article {Carod-Artal:August 2006:0333-1024:934, author = "Carod-Artal, FJ", author = "da Silveira Ribeiro, L", author = "Braga, H", author = "Kummer, W", author = "Mesquita, HM", author = "Vargas, AP", title = "Prevalence of patent foramen ovale in migraine patients with and without aura compared with stroke patients. A transcranial Doppler study", journal = "Cephalalgia", volume = "26", year = "August 2006", abstract = "Carod-Artal FJ, da Silveira Ribeiro L, Braga H, Kummer W, Mesquita HM & Vargas AP. Prevalence of patent foramen ovale in migraine patients with and without aura compared with stroke patients. A transcranial Doppler study. Cephalalgia 2006; 26:934-939. London. ISSN 0333-1024

The aim of this study was to investigate the prevalence of patent foramen ovale (PFO) in a consecutive unselected cohort of migraine patients (with and without aura) and compare it with a group of ischaemic young and elderly stroke patients. One hundred and forty-one migraine patients were compared with 330 stroke patients (130 young patients; 200 elderly patients) selected from our hospital stroke data bank. PFO was assessed with transcranial Doppler sonography with i.v. injection of agitated saline. The prevalence of PFO was 51.7% in migraine with aura (MA) patients, 33.7% in migraine without aura (MoA) patients, 33.8% in young stroke patients and 20.5% in elderly stroke patients (P < 0.001). The prevalence of PFO in cryptogenic stroke in young and elderly stroke patients was, respectively, 41.1% and 25% (P = 0.04). The difference between MA and MoA patients was significant (odds ratio = 2.1). The prevalence of PFO in MA patients is higher than in MoA patients and in young cryptogenic stroke patients.", pages = "934-939(6)", url = "http://www.ingentaconnect.com/content/bsc/cha/2006/00000026/00000008/art00005" doi = "doi:10.1111/j.1468-2982.2006.01156.x" }