Pigment dispersion syndrome and pigmentary glaucoma - a major review

Authors: Niyadurupola, Nuwan; Broadway, David C

Source: Clinical & Experimental Ophthalmology, Volume 36, Number 9, December 2008 , pp. 868-882(15)

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Abstract:

Pigment dispersion syndrome (PDS) is an interesting condition that can lead to secondary open angle glaucoma. Pigmentary glaucoma is primarily a disease of young people, myopes and men. PDS is characterized by the presence of Krukenberg spindles, iris trans-illumination defects, trabecular meshwork pigmentation and backward bowing of the iris. Posterior bowing of the iris causes rubbing of the pigmented iris epithelium against lens structures, liberation of pigment and trabecular meshwork changes that result in reduced aqueous outflow with the risk of glaucoma. Peripheral laser iridotomy can reverse backward bowing of the iris and may prevent progression of pigmentary glaucoma.

Keywords: pigment dispersion syndrome; ocular hypertension; pigmentary glaucoma; peripheral laser iridotomy

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1442-9071.2009.01920.x

Publication date: 2008-12-01