Beta radiation as an adjunct to low-risk trabeculectomy

Authors: Barnes, Rachel M; Mora, Justin S; Best, Stephen J

Source: Clinical & Experimental Ophthalmology, Volume 28, Number 4, August 2000 , pp. 259-262(4)

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Abstract:

Purpose: To assess a single dose of intraoperative beta radiation used to enhance the success rate of trabeculectomy in a population of low-risk glaucoma patients in whom antimetabolites might not be indicated.

Methods: A prospective randomized trial of 65 eyes was designed, with 31 eyes receiving 750 rads of intraoperative beta radiation (group 1), and 34 eyes receiving no supplementation (group 2).

Results: Mean follow-up time was 24 months. Mean postoperative intraocular pressure was 12.2 mmHg in group 1, and 13.7 mmHg in group 2 (P = 0.16). Mean decrease in intraocular pressure was 10.3 mmHg in group 1, and 9.3 mmHg in group 2 (P = 0.49). The two groups were not significantly different in terms of surgical complications.

Conclusion: For this population of low-risk patients, there was no significant difference in outcome after applications of a single intraoperative dose of beta radiation.

Keywords: beta radiation; glaucoma; trabeculectomy

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1442-9071.2000.00317.x

Publication date: 2000-08-01