Lesions of pemphigus vulgaris on irradiated skin

Authors: Aguado, L.; Marquina, M.; Pretel, M.; Ruiz-Carrillo, G.; España, A.

Source: Clinical & Experimental Dermatology, Volume 34, Number 5, July 2009 , pp. e148-e150(3)

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Abstract:

Summary

Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy. We report a patient with a history of microprolactinoma and PV, who had only oral lesions from the beginning of her illness but 2 months after treatment with radiotherapy for a breast neoplasia, developed skin lesions limited to the irradiated area. Over the following few months, she also developed autoantibodies against Dsg1.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1365-2230.2008.03084.x

Publication date: 2009-07-01