Pemphigus foliaceus with prominent neutrophilic pustules initially presenting as erythroderma

Authors: Miyakura, T.; Yamamoto, T.¹; Okubo, Y.; Ishii, N.²; Oyama, B.²; Hashimoto, T.²; Tsuboi, R.

Source: Clinical & Experimental Dermatology, Volume 34, Number 5, July 2009 , pp. e46-e49(4)

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Abstract:

Summary

We report a 64-year-old man who presented with generalized erythroderma and erosions. The erythroderma improved generally as a result of systemic prednisolone treatment. After treatment, however, the patient developed annular erythema with tiny pustules. Histopathology, ELISA and immunoblot analysis showed the disease to be pemphigus foliaceus (PF) with prominent neutrophilic pustules. To our knowledge, this is the first known case of PF with prominent neutrophilic pustules presenting as erythroderma.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1365-2230.2008.03190.x

Affiliations: 1: Fukushima Medical University, Fukushima, Japan 2: Kurume University School of Medicine, Kurume, Japan

Publication date: 2009-07-01