Cutaneous Rosai-Dorfman disease

Authors: CHILD¹; FULLER¹; SALISBURY²; HIGGINS¹

Source: Clinical & Experimental Dermatology, Volume 23, Number 1, January 1998 , pp. 40-42(3)

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Abstract:

We report a patient with purely cutaneous Rosai-Dorfman disease (RDD) who presented with a solitary, asymptomatic plaque on the back of her left thigh, with characteristic, large histiocytoid cells exhibiting emperipolesis histologically. Cutaneous lesions occur in 27% of patients with lymph node involvement in RDD however purely cutaneous disease has only been reported on 18 previous occasions. The aetiology is unknown, although it is thought to be a reactive disorder rather than neoplastic, possibly an immunological response to an infectious agent.

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1365-2230.1998.00312.x

Affiliations: 1: Department of Dermatology, King's College Hospital, London SE5 9RS, U.K., 2: Department of Histopathology, King's College Hospital, London SE5 9RS, U.K.

Publication date: 1998-01-01