ISSN 1462-8910 (Print); ISSN 1463-1318 (Online)
Faecal incontinence: the ‘Cinderella’ disorder
Scholefield, John H.; Walker, David
A randomised, controlled, crossover study to investigate the safety and response of 1R,2S‐methoxamine hydrochloride (NRL001) on anal function in healthy volunteers
Simpson, J. A. D.; Bush, D.; Gruss, H. J.; Jacobs, A.; Pediconi, C.; Scholefield, J. H.
Randomised clinical trial: study of escalating doses of NRL001 given in rectal suppositories of different weights
Bell, D.; Pediconi, C.; Jacobs, A.
A randomised, controlled, crossover study to investigate the pharmacodynamics, pharmacokinetics and safety of 1R,2S‐methoxamine hydrochloride (NRL001) in healthy elderly subjects
Bell, D.; Duffin, A.; Gruss, H. J.; Pediconi, C.; Jacobs, A.
A double‐blind, placebo‐controlled, randomised, parallel‐group, dose‐escalating, repeat dose study in healthy volunteers to evaluate the safety, tolerability, pharmacodynamic effects and pharmacokinetics of the once daily rectal application of NRL001 suppositories
for 14 days
Bell, D.; Duffin, A.; Jacobs, A.; Pediconi, C.; Gruss, H. J.
Meta‐analysis for cardiovascular effects of NRL001 after rectal application in healthy volunteers
Gruss, H. J.; Pediconi, C.; Jacobs, A.
Libertas: rationale and study design of a multicentre, Phase II, double–blind, randomised, placebo–controlled investigation to evaluate the efficacy, safety and tolerability of locally applied NRL001 in patients with faecal incontinence
Siproudhis, L.; Jones, D.; Ng Kwet Shing, R.; Walker, D.; Scholefield, J. H.; the Libertas Study Consortiumcodi12546-cr-0006