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Maternal screening and postpartum vaccination for measles infection in Japan: a cohort study

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Abstract:

Please cite this paper as: Shoda A, Hayashi M, Takayama N, Oshima K, Nishikawa M, Okazaki T, Negishi M, Hayashida S, Watanabe H, Inaba N. Maternal screening and postpartum vaccination for measles infection in Japan: a cohort study. BJOG 2011;118:88–92.

We investigated the prevalence of measles-sensitive pregnant women and the clinical usefulness of measles vaccination in postpartum women. Measles antibody levels were measured in 751 pregnant women. Forty-four women were vaccinated postpartum, and screened for antibody levels and adverse effects 1 month after vaccination. The prevalence of measles-sensitive pregnant women was 10–20%, with the highest prevalence in those under 24 years of age. Almost all (97.7%) vaccinated women acquired immunity, and did not show any adverse effects. Serum measles antibody levels should be determined in all pregnant women as a screening tool, and sensitive women should be vaccinated immediately after delivery.

Keywords: Measles antibody; measles infection; measles vaccination; pregnancy

Document Type: Short Communication

DOI: http://dx.doi.org/10.1111/j.1471-0528.2010.02764.x

Affiliations: 1: Department of Obstetrics and Gynaecology, Dokkyo Medical University, Tochigi, Japan 2: Department of Paediatrics, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan

Publication date: January 1, 2011

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