Skip to main content

Obesity as a risk factor for development and poor prognosis of breast cancer

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

The evidence that obesity adversely affects women’s health is overwhelming and indisputable. The risk of postmenopausal breast cancer increases with obesity; measured as weight gain, body mass index, waist–hip ratio or percent body fat. It is also established that obesity is associated with poor prognosis of breast cancer. This review examines in detail the possible mechanisms by which obesity causes poor prognosis of breast cancer such as estrogenic activity, advanced or more aggressive disease at diagnosis and high likelihood of both local and systemic treatment failure. After careful consideration of the available evidence, the author concludes that obesity contributes towards development and poor prognosis of breast cancer; therefore, weight management should be an integral part of any strategy to prevent and improve the outcome of breast cancer.

Keywords: Body mass index; body weight; breast neoplasm; obesity; prognosis

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1471-0528.2006.01021.x

Publication date: 2006-10-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more