Interferon-alpha may restore sensitivity to tyrosine-kinase inhibitors in Philadelphia chromosome positive acute lymphoblastic leukaemia with F317L mutation

Authors: Potenza, Leonardo1; Volzone, Francesco1; Riva, Giovanni1; Soverini, Simona2; Martinelli, Silvia1; Iacobucci, Ilaria2; Gnani, Alessandra2; Barozzi, Patrizia1; Forghieri, Fabio1; Morselli, Monica1; Zanetti, Eleonora1; Maccaferri, Monica1; Baccarani, Michele2; Martinelli, Giovanni2; Torelli, Giuseppe1; Luppi, Mario1

Source: British Journal of Haematology, Volume 146, Number 2, July 2009 , pp. 227-230(4)

Publisher: Wiley-Blackwell

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Keywords: Philadelphia chromosome; acute lymphoblastic leukaemia; BCR-ABL point mutation; resistance; interferon alpha

Document Type: Correspondence

DOI: http://dx.doi.org/10.1111/j.1365-2141.2009.07747.x

Affiliations: 1: Section of Haematology, Department of Oncology, Haematology and Respiratory Diseases University of Modena and Reggio Emilia, Modena 2: Institute of Haematology and Medical Oncology “L. e A. Seragnoli”, University of Bologna, Bologna, Italy., Email: mario.luppi@unimore.it

Publication date: 2009-07-01

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