TAFI antigen and D-dimer levels during normal pregnancy and at delivery

Authors: Chabloz, Patrick¹; Reber, Guido²; Boehlen, Françoise²; Hohlfeld, Patrick¹; de Moerloose, Philippe²

Source: British Journal of Haematology, Volume 115, Number 1, October 2001 , pp. 150-152(3)

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Abstract:

We have investigated whether the levels of thrombin-activatable fibrinolysis inhibitor (TAFI) were correlated withd-dimer levels during pregnancy and at delivery. From the 10th week of pregnancy to delivery, 519 samples from 144 women (mean age 29·3 ± 5, range 19-43) were obtained. We confirm the gradual increase ofd-dimer levels, and provide reference intervals ford-dimer measurements throughout normal pregnancy. TAFI levels increased moderately during pregnancy but no inverse correlation withd-dimer levels was observed.

Keywords: TAFI; d-dimer; pregnancy

Document Type: Research article

Affiliations: 1: Department of Gynaecology and Obstetrics, Lausanne University Hospital, Lausanne, and 2: Division of Angiology and Haemostasis, Geneva University Hospital, Geneva, Switzerland

Publication date: 2001-10-01