Inadequacies in the postnatal management of fetomaternal alloimmune thrombocytopenia (FMAIT)

Authors: Murphy M.F.^{2, *}; Verjee S.¹; Greaves M.³

Source: British Journal of Haematology, Volume 105, Number 1, 1 April 1999 , pp. 123-126(4)

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Abstract:

93 (31%) of the 301 Haematology Departments in the U.K. responded to a questionnaire about the postnatal management of fetomaternal alloimmune thrombocytopenia (FMAIT). The number of reported cases of FMAIT was less than half than that estimated from its known incidence, suggesting that the condition is under-recognized. There was a consensus that the optimal approach to postnatal management is to transfuse compatible platelets promptly. However, a number of problems in the delivery of treatment were identified, including an apparent lack of awareness of the potential seriousness of the condition amongst clinical staff, and the availability of HPA-1a negative platelets.

Keywords: thrombocytopenia; alloimmune; fetomaternal; management; postnatal

Language: English

Document Type: Short communication

Affiliations: 1: National Blood Service 2: Department of Haematology, Oxford Radcliffe Hospital, Oxford 3: Department of Medicine and Therapeutics, University of Aberdeen *

Publication date: 1999-04-01