Skip to main content

Severe digital necrosis in an elderly patient with heterozygous factor V Leiden mutation

Buy Article:

$43.00 plus tax (Refund Policy)

We report an 81-year-old female with a heterozygous factor V Leiden mutation who developed purpura fulminans. Digital necrosis, a characteristic clinical feature of purpura fulminans was prominent. Purpura fulminans is more common in children and adult cases are rare. Of eight reported cases of purpura fulminans resulting from a heterozygous factor V Leiden mutation recorded in the literature, only two were in adults: 40 and 42 years of age, respectively. This is the first report of this condition arising in a patient in her eighties.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: digital necrosis; factor V Leiden; protein C; purpura fulminans

Document Type: Research Article

Affiliations: 1: Haematology and 2: Pathology, Royal Gwent Hospital, Cardiff Road, Newport NP9 2UB, U.K. 3: Departments of Dermatology,

Publication date: 2000-12-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more