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Paracoccidioidomycosis (South American blastomycosis) successfully treated with terbinafine: first case report

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We describe a 63-year-old man who presented with painful malodorous lesions in the perianal, perineal and scrotal regions. Following definitive diagnosis of paracoccidioidomycosis, he was treated initially with trimethoprim/sulphamethoxazole, but there was no clinical improvement. He then received terbinafine (Lamisil®) 250 mg twice daily for 6 months. There was rapid resolution of all lesions and complete relief of symptoms, without any associated side-effects. The patient remains clinically well and without any evidence of infection 2 years after discontinuation of terbinafine treatment.
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Keywords: paracoccidioidomycosis; terbinafine

Document Type: Research Article

Affiliations: Department of Dermatology, Venereology and Allergy, IESS University of Guayaquil, PO Box 09-01-8611, Guayaquil, Ecuador

Publication date: 2000-07-01

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