A double-blind, randomized, comparative trial of itraconazole versus terbinafine for 2 weeks in tinea capitis

Authors: Jahangir; Hussain; UL Hasan,; Haroon

Source: British Journal of Dermatology, Volume 139, Number 4, October 1998 , pp. 672-674(3)

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Abstract:

In this randomized, double-blind study, the efficacy and safety of oral itraconazole (n = 28) and terbinafine (n = 27), each given for 2 weeks, was compared in patients with tinea capitis. Trichophyton violaceum was the major pathogen in both groups (82.1% and 88.9%, respectively). The final evaluation at week 12 showed a cure rate of 85.7% and 77.8%, respectively (P > 0.05). Adverse events noted were mild and did not warrant discontinuation of therapy.

Document Type: Original article

DOI: http://dx.doi.org/10.1046/j.1365-2133.1998.02465.x

Affiliations: 1: Department of Dermatology, King Edward Medical College/Mayo Hospital, Lahore, Pakistan

Publication date: 1998-10-01