British Journal of Clinical Pharmacology

Editors' Report, December 2008
pp. 151-152(2)
Authors: Cohen, AF; Loke, YK; Lewis, LD; Schachter, M; Somogyi, A; Ritter, JM

Use of pharmacokinetic/ pharmacodynamic modelling for starting dose selection in first-in-human trials of high-risk biologics
pp. 153-160(8)
Author: Agoram, Balaji M.

Effectiveness and safety of short vs. long duration of antibiotic therapy for acute bacterial sinusitis: a meta-analysis of randomized trials
pp. 161-171(11)
Authors: Falagas, Matthew E.; Karageorgopoulos, Drosos E.; Grammatikos, Alexandros P.; Matthaiou, Dimitrios K.

Oxycodone is associated with dose-dependent QTc prolongation in patients and low-affinity inhibiting of hERG activity in vitro
pp. 172-179(8)
Authors: Fanoe, Søren; Jensen, Gorm Boje; Sjøgren, Per; Korsgaard, Mads P. G.; Grunnet, Morten

Tolerability, pharmacokinetics and night-time effects on postural sway and critical flicker fusion of gaboxadol and zolpidem in elderly subjects
pp. 180-190(11)
Authors: Boyle, Julia; Danjou, Philippe; Alexander, Robert; Calder, Nicole; Gargano, Cynthia; Agrawal, Nancy; Fu, Irong; McCrea, Jacqueline B.; Murphy, M. Gail

In vivo comparison of the relative systemic bioavailability of fluticasone propionate from three anti-static spacers and a metered dose inhaler
pp. 191-198(8)
Authors: Nair, Arun; Menzies, Daniel; Hopkinson, Pippa; McFarlane, Lesley; Lipworth, Brian J.

Moclobemide monotherapy vs. combined therapy with valproic acid or carbamazepine in depressive patients: a pharmacokinetic interaction study
pp. 199-208(10)
Authors: Rakic Ignjatovic, Anita; Miljkovic, Branislava; Todorovic, Dejan; Timotijevic, Ivana; Pokrajac, Milena

Influence of domperidone on pharmacokinetics, safety and tolerability of the dopamine agonist rotigotine
pp. 209-215(7)
Authors: Braun, Marina; Cawello, Willi; Boekens, Hilmar; Horstmann, Rolf

Population pharmacokinetics of intravenous pantoprazole in paediatric intensive care patients
pp. 216-227(12)
Authors: Pettersen, Géraldine; Mouksassi, Mohamad-Samer; Théorêt, Yves; Labbé, Line; Faure, Christophe; Nguyen, Bao; Litalien, Catherine

The use and potential abuse of anticholinergic antiparkinson drugs in Norway: a pharmacoepidemiological study
pp. 228-233(6)
Authors: Gjerden, Pål; Bramness, Jørgen G.; Slørdal, Lars

Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy
pp. 234-241(8)
Authors: Devold, Helene M.; Molden, Espen; Skurtveit, Svetlana; Furu, Kari

An increase in the prevalence of type 1 and 2 diabetes in children and adolescents: results from prescription data from a UK general practice database
pp. 242-249(8)
Authors: Hsia, Yingfen; Neubert, Antje C.; Rani, Fariz; Viner, Russell M.; Hindmarsh, Peter C.; Wong, Ian C. K.

The availability of prescription-only analgesics purchased from the internet in the UK
pp. 250-254(5)
Authors: Raine, Connie; Webb, David J.; Maxwell, Simon R. J.

Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme
pp. 255-261(7)
Authors: Wang, Xue-Ding; Li, Jia-Li; Su, Qi-Biao; Guan, Su; Chen, Jie; Du, Jun; He, Yu-Wen; Zeng, Jun; Zhang, Jin-Xin; Chen, Xiao; Huang, Min; Zhou, Shu-Feng

High voriconazole trough levels in relation to hepatic function: how to adjust the dosage?
pp. 262-263(2)
Authors: Alffenaar, Jan-Willem C.; de Vos, Tessa; Uges, Donald R. A.; Daenen, Simon M. G. J.

Aggrenox (Asasantin retard)-induced Stevens-Johnson syndrome
pp. 264-265(2)
Authors: Jao, Tun; Tsai, Tsung-Hua; Jeng, Jiann-Shing

Unexplained severe hypoglycaemia in hospital: a difficult diagnostic challenge
pp. 266-267(2)
Authors: Walker, Jonathan; White, Rebecca; Vale, Allister; Elliott, Simon; Wass, John; Reynolds, John

The Science of Marijuana, 2nd edn
pp. 268-268(1)

Translation Section
pp. 269-275(7)

Erratum
pp. 276-276(1)