British Journal of Clinical Pharmacology

Editors' view January 2008
pp. 1-2(2)
Author: Ritter, J. M.

Overview of the human pharmacokinetics of recombinant activated factor VII
pp. 3-11(9)
Authors: Klitgaard, Thomas; Nielsen, Tina G.

Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions
pp. 12-21(10)
Authors: Muchohi, Simon N.; Obiero, Kenneth; Newton, Charles R. J. C.; Ogutu, Bernhards R.; Edwards, Geoffrey; Kokwaro, Gilbert O.

The pharmacokinetics and effects of a long-acting preparation of superoxide dismutase (PC-SOD) in man
pp. 22-29(8)
Authors: Broeyer, F. J. F.; van Aken, B. E.; Suzuki, J.; Kemme, M. J. B.; Schoemaker, H. C.; Cohen, A. F.; Mizushima, Y.; Burggraaf, J.

Population pharmacokinetic analysis of carboxyhaemoglobin concentrations in adult cigarette smokers
pp. 30-39(10)
Authors: Cronenberger, Carol; Mould, Diane R.; Roethig, Hans-Juergen; Sarkar, Mohamadi

Effect of theophylline on the rate of moderate to severe exacerbations among patients with chronic obstructive pulmonary disease
pp. 40-50(11)
Authors: Cyr, Marie-Christyne; Beauchesne, Marie-France; Lemière, Catherine; Blais, Lucie

Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism
pp. 51-59(9)
Authors: Schwedhelm, Edzard; Maas, Renke; Freese, Ralf; Jung, Donald; Lukacs, Zoltan; Jambrecina, Alen; Spickler, William; Schulze, Friedrich; Böger, Rainer H.

Interindividual variability in the concentration-effect relationship of antilymphocyte globulins—a possible influence of FcγRIIIa genetic polymorphism
pp. 60-68(9)
Authors: Ternant, David; Büchler, Matthias; Bénéton, Maud; Alván, Gunnar; Ohresser, Marc; Touchard, Guy; Hurault de Ligny, Bruno; Toupance, Olivier; Watier, Hervé; Lebranchu, Yvon; Paintaud, Gilles

IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations
pp. 69-77(9)
Authors: Haglund, Sofie; Taipalensuu, Jan; Peterson, Curt; Almer, Sven

No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone
pp. 78-86(9)
Authors: Kalliokoski, Annikka; Neuvonen, Mikko; Neuvonen, Pertti J.; Niemi, Mikko

Time-dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants
pp. 87-97(11)
Authors: Polasek, Thomas M.; Miners, John O.

Interaction between midazolam and clarithromycin in the elderly
pp. 98-109(12)
Authors: Quinney, Sara K.; Haehner, Barbara D.; Rhoades, Melissa B.; Lin, Zhen; Gorski, J. Christopher; Hall, Stephen D.

Exposure-response analysis reveals that clinically important toxicity difference can exist between bioequivalent carbamazepine tablets
pp. 110-122(13)
Authors: Tothfalusi, Laszlo; Speidl, Szilvia; Endrenyi, Laszlo

Issues concerning the use of hormone replacement therapy and risk of fracture: a population-based, nested case-control study
pp. 123-129(7)
Authors: Corrao, Giovanni; Zambon, Antonella; Nicotra, Federica; Conti, Valentino; Nappi, Rossella E.; Merlino, Luca

Relationship between polypharmacy and underprescribing
pp. 130-133(4)
Authors: Kuijpers, Mascha A. J.; van Marum, Rob J.; Egberts, Antoine C. G.; Jansen, Paul A. F.

The CYP2D6 polymorphism in relation to the metabolism of amitriptyline and nortriptyline in the Faroese population
pp. 134-138(5)
Authors: Halling, Jónrit; Weihe, Pál; Brosen, Kim

A comparison of serum antivenom concentrations after intravenous and intramuscular administration of redback (widow) spider antivenom
pp. 139-143(5)
Authors: Isbister, Geoffrey K.; O'Leary, Margaret; Miller, Mark; Brown, Simon G. A.; Ramasamy, Sharmaine; James, Rosemary; Schneider, Jennifer S.

Drug-drug interactions - a preventable patient safety issue?
pp. 144-146(3)
Authors: Strandell, Johanna; Bate, Andrew; Lindquist, Marie; Edwards, I Ralph

Statins and phenytoin interact - a case history
pp. 147-148(2)
Authors: Tan, Kit Mun; Kelly, John G.; McGarry, Kathleen

Neutropenia induced in a patient by treatment with ritodrine: in vitro evaluation of myeloid progenitor colony-forming cells
pp. 149-150(2)
Authors: Tsukimori, Kiyomi; Morokuma, Seiichi; Yoshimura, Takazumi; Muta, Koichiro; Wake, Norio