Regional variations in community consumption of antibiotics in Hungary, 1996–2003

Authors: Matuz, Maria; Benko, Ria¹; Doro, Peter¹; Hajdu, Edit²; Nagy, Gabor³; Nagy, Erzsebet²; Monnet, Dominique L.⁴; Soos, Gyongyver¹

Source: British Journal of Clinical Pharmacology, Volume 61, Number 1, January 2006 , pp. 96-100(5)

Publisher: Blackwell Publishing

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Abstract:

Aims

To study regional differences and identify determinants of antibiotic consumption in ambulatory care in Hungary. Methods

Regional distribution-based antibiotic sales data were converted into a number of defined daily doses (DDD) per 1000 inhabitant-days. Correlations were assessed with the Spearman rank test. Results

There were large and stable interregional differences in antibiotic consumption. They were associated with socio-economic determinants, e.g. the population receiving free access to medicines and receiving regular social assistance. Conclusions

More detailed studies are needed to better understand the determinants of antibiotic use in these specific patient populations and to identify additional determinants at regional level.

Keywords: antibacterials; community consumption; determinants of antibiotic use; drug utilization; regional differences

Document Type: Research article

DOI: 10.1111/j.1365-2125.2005.02525.x

Affiliations: 1: Department of Clinical Pharmacy and 2: Department of Clinical Microbiology, University of Szeged and 3: IMS PharmMIS Consulting Company, Budapest, Hungary, and 4: National Centre for Antimicrobials and Infection Control, Statens Serum Institut, Copenhagen, Denmark