British Journal of Clinical Pharmacology

Today's science, tomorrow's medicines
pp. 1-4(4)
Authors: Aronson, Jeffrey K.; Lennard, Martin S.; Ritter, James M.; Baber, Nigel S.; Begg, Evan J.; Lewis, Lionel D.

N-acetylcysteine – passe-partout or much ado about nothing?
pp. 5-15(11)
Author: Aitio, Mirja-Liisa

Brain histamine H₁ receptor occupancy of orally administered antihistamines measured by positron emission tomography with ¹¹C-doxepin in a placebo-controlled crossover study design in healthy subjects: a comparison of olopatadine and ketotifen
pp. 16-26(11)
Authors: Tashiro, Manabu; Mochizuki, Hideki; Sakurada, Yumiko; Ishii, Kenji; Oda, Keiichi; Kimura, Yuichi; Sasaki, Toru; Ishiwata, Kiichi; Yanai, Kazuhiko

µ-Opiate receptor agonists – a new pharmacological approach to prevent motion sickness?
pp. 27-30(4)
Authors: Otto, Bärbel; Riepl, Rudolf L.; Otto, Carsten; Klose, Joachim; Enck, Paul; Klosterhalfen, Sibylle

Gastrointestinal transit, release and plasma pharmacokinetics of a new oral budesonide formulation
pp. 31-38(8)
Authors: Brunner, M.; Ziegler, S.; Di Stefano, A. F. D.; Dehghanyar, P.; Kletter, K.; Tschurlovits, M.; Villa, R.; Bozzella, R.; Celasco, G.; Moro, L.; Rusca, A.; Dudczak, R.; Müller, M.

Limited predictability of amikacin clearance in extreme premature neonates at birth
pp. 39-48(10)
Authors: Allegaert, Karel; Anderson, Brian J.; Cossey, Veerle; Holford, Nicholas H. G.

The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide
pp. 49-57(9)
Authors: Bidstrup, Tanja Busk; Damkier, Per; Olsen, Anette Kristensen; Ekblom, Marianne; Karlsson, Anders; Brøsen, Kim

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics
pp. 58-69(12)
Authors: Grimm, Scott W.; Richtand, Neil M.; Winter, Helen R.; Stams, Karen R.; Reele, Stots B.

Effect of rifampicin on the pharmacokinetics of pioglitazone
pp. 70-78(9)
Authors: Jaakkola, Tiina; Backman, Janne T.; Neuvonen, Mikko; Laitila, Jouko; Neuvonen, Pertti J.

Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance
pp. 79-86(8)
Authors: Theunissen, Eef L.; Vermeeren, Annemiek; Ramaekers, Johannes G.

Thiazide diuretic prescription and electrolyte abnormalities in primary care
pp. 87-95(9)
Authors: Clayton, J. A.; Rodgers, S.; Blakey, J.; Avery, A.; Hall, I. P.

Regional variations in community consumption of antibiotics in Hungary, 1996–2003
pp. 96-100(5)
Authors: Matuz, Maria; Benko, Ria; Doro, Peter; Hajdu, Edit; Nagy, Gabor; Nagy, Erzsebet; Monnet, Dominique L.; Soos, Gyongyver

Quantification of infant exposure to celecoxib through breast milk
pp. 101-104(4)
Authors: Gardiner, Sharon J.; Doogue, Matthew P.; Zhang, Mei; Begg, Evan J.

Reply: The evaluation of data mining methods for the simultaneous and systematic detection of safety signals in large databases: lessons to be learned
pp. 105-113(9)
Authors: Levine, Jonathan G.; Tonning, Joseph M.; Szarfman, Ana

Erratum
pp. 114-114(1)

Response to letter by Levine et al.
pp. 115-117(3)
Authors: Hauben, Manfred; Reich, Lester

Incidental events in spontaneous reports – a proposal for filtering ’noise’
pp. 118-119(2)
Author: Walsh, Louisa