Abstract:A new type of benzothiazolinone derivative with potential pharmacological activity, viz. 6-(3,4-difluorobenzoyl)-3-[2-(4-pyridyl)ethyl]-1,3-benzothiazol-2(3H)-one, C21H14F2N2O2S, has been prepared and studied by NMR, IR and single-crystal X-ray diffraction techniques. The molecule is not planar, the pyridine and difluorobenzene moieties being located above and below the benzothiazole ring system. The carbonyl O atoms are involved in an intramolecular hydrogen-bond-type interaction.
Document Type: Research Article
Publication date: October 1, 2004