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2′-(4-Fluoro­phenyl)-[1,2,3]­triazolo[4′,5′:16,17]­androst-5-en-3-ol methanol hemisolvate

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Abstract:

The asymmetric unit of the title compound, C25H30FN3O·0.5CH3OH, contains four symmetry-independent steroid and two methanol mol­ecules. The conformations of the independent steroid mol­ecules are very similar. Intermolecular O—H…O hydrogen bonds create two independent chains, each of which links two of the independent steroid mol­ecules plus one methanol mol­ecule via a co-operative O—H…O—H…O—H pattern. Intermolecular C—H…O and C—H…F interactions are also observed.

Document Type: Research Article

DOI: http://dx.doi.org/10.1107/S0108270104008455

Publication date: June 1, 2004

bsc/ayc/2004/00000060/00000006/art00035
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