@article {Langer:December 2007:0004-8461:532, author = "Langer,", author = "Neidl van Gorkom,", author = "Al Kaabi,", author = "Torab,", author = "Czechowski,", author = "Nagi,", author = "Ashish,", title = "Comparison of two imaging protocols for acute stroke: Unenhanced cranial CT versus a multimodality cranial CT protocol with perfusion imaging", journal = "Australasian Radiology", volume = "51", year = "December 2007", abstract = "Summary
The aim of the study was to validate a multimodality cranial computed tomography (CCT) protocol for patients with acute stroke in the United Arab Emirates as a basic imaging procedure for a stroke unit. Therefore, a comparative study was conducted between two groups: retrospective, historical group 1 with early unenhanced CCT and prospective group 2 undergoing a multimodality CCT protocol. Follow-up unenhanced CCT >48 h served as gold standard in both groups. Group 1: Early unenhanced CCT of 50 patients were evaluated retrospectively, using Alberta Stroke Program Early CT Score, and compared with the definite infarction on follow-up CCT. Group 2: 50 patients underwent multimodality CCT (unenhanced CCT, perfusion studies: cerebral blood flow, cerebral blood volume, mean transit time and CT angiography) <8 h after clinical onset and follow-up studies. Modified National Institute of Health Stroke Scale was used clinically in both groups. Group 1 showed 38 men, 12 women, clinical onset 2-8 h before CCT and modified National Institute of Health Stroke Scale 0-28. Group 2 included 38 men, 12 women, onset 3-8 h before CCT, modified National Institute of Health Stroke Scale 0-28. Sensitivity was 58.3% in group 1 and 84.2% in group 2. Computed tomography angiography detected nine intracranial occlusions/stenoses. The higher sensitivity of the multimodality CCT protocol justifies its use as a basic diagnostic tool for the set-up of a first-stroke unit in the United Arab Emirates.", pages = "532-537(6)", url = "http://www.ingentaconnect.com/content/bsc/ara/2007/00000051/00000006/art00006" doi = "doi:10.1111/j.1440-1673.2007.01901.x" }