Radiologically placed temporary hepatic artery catheter for treatment of liver cancer

Authors: Gananadha, S¹; Yan, TDB¹; Zhao, J¹; Clingan, P²; Glenn, D³; Morris, DL¹

Source: Australasian Radiology, Volume 49, Number 5, October 2005 , pp. 396-399(4)

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Abstract:

Summary

Hepatic artery infusion (HAI) chemotherapy is associated with higher response rates compared to systemic chemotherapy in those patients with unresectable liver malignancies. Operative hepatic artery catheter (HAC) insertion has significant morbidity and mortality, especially in patients with high-volume disease, some of whom may not respond to HAI chemotherapy. We report our experience in 45 patients with high-volume liver disease who were initially treated with HAI chemotherapy via a radiologically placed temporary HAC to try to select the responders who then went on to have an operative HAC. In these 45 patients who had 62 radiologically placed HAC, we found very few major complications, and certainly no complications such as cholecystitis, vascular or malperfusion problems.

Keywords: drug therapy; hepatic artery; liver neoplasms; radiology

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1440-1673.2005.01501.x

Affiliations: 1: University of New South Wales Department of Surgery, 2: Cancer Care Centre and 3: Department of Radiology, St George Hospital, Sydney, New South Wales, Australia

Publication date: 2005-10-01