IngentaConnect Double stenting of oesophagus and airways in palliative treatment...

Authors: LECLEIRE, S.¹; ANTONIETTI, M.¹; DI FIORE, F.¹; BEN-SOUSSAN, E.¹; BOTA, S.²; HELLOT, M.-F.³; THIBERVILLE, L.²; MICHEL, P.¹; LEREBOURS, E.¹; DUCROTTÉ, P.¹

Source: Alimentary Pharmacology & Therapeutics, Volume 25, Number 8, April 2007 , pp. 955-963(9)

Publisher: Blackwell Publishing

Abstract:

SUMMARY Background

Double stenting of oesophagus and airways may be required in palliative treatment of patients with locally advanced oesophageal cancer. Aim

To assess feasibility, efficacy and complications occurring in patients with locally advanced oesophageal cancer receiving both oesophagus and airways stenting. Methods

In one single centre between 1997 and 2005, among 180 patients with locally advanced oesophageal cancer treated by the palliative placement of a self-expanding metal stent, patients requiring double stenting of oesophagus and airways were identified. Clinical efficacy, complications and survival were retrospectively collected. Results

Fifteen patients (8.3% of 180) required a double stenting at follow-up. Symptomatic efficacy of oesophagus and airways stenting was 86.7% for dysphagia and 100% for dyspnoea. Median survival after the second stent insertion was 99 days. Life-threatening early complications occurred in three patients after double stenting (20%), including two deaths following oesophageal perforation and massive haemoptysis, respectively. Procedure-related mortality was 13.3%. Conclusions

Double stenting of oesophagus and airways is feasible in patients with locally advanced oesophageal cancer, with a relevant clinical efficacy. However, early major complications including procedure-related death may occur in as many as 20% of patients. This treatment should be reserved to very selected patients with severe symptoms and end-stage disease.

Document Type: Research article

DOI: 10.1111/j.1365-2036.2007.03280.x

Affiliations: 1: Department of Hepato-Gastroenterology and Nutrition, Rouen University Hospital & ADEN-EA3234/IFRMP23, Institute for Biomedical Research 2: Department of Pneumology 3: Department of Biostatistics, Rouen University Hospital, Rouen, France

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$50.39 plus tax Refund Policy

Double stenting of oesophagus and airways in palliative treatment of patients with oesophageal cancer is efficient but associated with a high morbidity