@article {ARMSTRONG:January 2007:0953-0673:185,
	author = "ARMSTRONG, D.",
	author = "JAMES, C.",
	author = "CAMACHO, F.",
	author = "CHEN, Y.",
	author = "HORBAY, G. L. A.",
	author = "TEIXEIRA, B.",
	author = "HUSEIN-BHABHA, F. A.",
	title = "Oral rabeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects",
	journal = "Alimentary Pharmacology & Therapeutics",
	volume = "25",
	year = "January 2007",
	abstract = "Summary Background <P></P>Intravenous pantoprazole is often administered inappropriately to hospitalized patients who can take oral medications. Aim <P></P>To compare the antisecretory effects of oral rabeprazole and intravenous pantoprazole in healthy subjects. Methods <P></P>In a double-blind, double-dummy, two-way crossover study, 38 <I>Helicobacter pylori</I>-negative volunteers were randomized to oral rabeprazole 20&#8201;mg or intravenous pantoprazole 40&#8201;mg daily for 3&#8201;days followed, after a 14-day washout period by the comparator treatment. Intragastric pH was recorded continuously for 24&#8201;h at baseline and on days 1 and 3 of each treatment period. Results <P></P>The mean (95&#37; CI) percentage of the 24-h recording with gastric pH &#62;4 was higher with rabeprazole than with pantoprazole on day 1: 37.7&#37; (30.6-44.8&#37;) vs. 23.9&#37; (20.0-27.8). The mean percentage times with pH &#62;3 and &#62;4 for all intervals assessed were greater and the median 24-h intragastric pH values were higher with rabeprazole than with pantoprazole on days 1 and 3. The mean acidity index was lower with rabeprazole on days 1 and 3. Conclusions <P></P>Oral rabeprazole 20&#8201;mg produced greater acid suppression than intravenous pantoprazole 40&#8201;mg. Therefore, it may be an appropriate and effective alternative in patients who can take oral medication.",
	pages = "185-196(12)",
	url = "http://www.ingentaconnect.com/content/bsc/apt/2007/00000025/00000002/art00008"
	doi = "doi:10.1111/j.1365-2036.2006.03160.x"
}