Authors: PANDOLFINO, J. E.¹; GHOSH, S.¹; ZHANG, Q.¹; HEATH, M.²; BOMBECK, T.²; KAHRILAS, P. J.¹

Source: Alimentary Pharmacology & Therapeutics, Volume 23, Number 2, January 2006 , pp. 331-340(10)

Publisher: Wiley-Blackwell

Abstract:

Summary Background 

Ambulatory pH monitoring is considered the gold standard for measuring oesophageal acid exposure, however, data comparing antimony and glass electrodes are limited. Aim 

To compare the accuracy of the Slimline antimony pH monitoring system and a conventional glass electrode catheter pH monitoring system during ambulatory conditions. Methods 

Eighteen subjects (13 males, 23–45 years) underwent simultaneous pH monitoring using the Slimline antimony pH electrode and MIC M3 glass pH electrode pH monitoring systems for 12 h. Acid exposure was analysed and compared by manual extraction of the data onto an excel spreadsheet. Results 

There was no statistical difference in the median per cent time the pH was <4 recorded by the two systems (Slimline, 3%, Glass MIC M3, 2%, P = 0.77) and the correlation was excellent (r = 0.84). The difference in recorded reflux events was also not significantly different between the two systems, with the absolute difference being 23 events (s.d., 26). Point-by-point discrepancy was 28% (s.d., 18%), however, the agreement in terms of reflex events was excellent (Kappa value, 0.89, s.d., 0.09). Conclusion 

Despite substantial point-by-point disagreement, the antimony Slimline pH catheter compares favourably to the Glass MIC M3 pH catheter in terms of measuring standard pH parameters.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1365-2036.2006.02750.x

Affiliations: 1: Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, IL, USA 2: Medtronic Inc., Shoreview, MN, USA

Publication date: 2006-01-01

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• By this author: PANDOLFINO, J. E. ;  GHOSH, S. ;  ZHANG, Q. ;  HEATH, M. ;  BOMBECK, T. ;  KAHRILAS, P. J.

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