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Pathologic acromioclavicular and sternoclavicular manifestations in rheumatoid arthritis, spondyloarthropathy and calcium phosphosphate deposition disease

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Abstract Aim: 

To assess if acromioclavicular and sternoclavicular joint findings share specificity with those of peripheral joints for distinguishing among the major forms of erosive arthritis. Methods: 

The clavicles from skeletons of 392 individuals with documented spondyloarthropathy, rheumatoid arthritis and calcium pyrophosphate deposition disease (CPDD) were macroscopically examined for erosion presence and character and for reactive new bone formation. Results: 

Examination of the bones of individuals with documented rheumatoid arthritis, spondyloarthropathy and calcium pyrophosphate deposition disease revealed specificity of acromioclavicular and sternoclavicular joint alterations for the underlying arthritis. Conclusions: 

Acromioclavicular and sternoclavicular erosions have equivalent diagnostic specificity to that of peripheral joints, facilitating diagnosis when erosions are not recognized in the latter. Such joint involvement was so common in individuals with other evidence of CPPD that its presence should suggest the likelihood of that diagnosis.

Keywords: acromioclavicular joint; calcium pyrophosphate deposition disease; rheumatoid arthritis; spondyloarthropathy; sternoclavicular joint

Document Type: Research Article


Affiliations: 1: Arthritis Center of North-east Ohio, Youngstown, North-eastern Ohio Universities College of Medicine, Rootstown, OH, Carnegie Museum of Natural History, Pittsburgh, PA and University of Kansas Museum of Natural History, Lawrence, KS, 2: Sarah Robinson, Cleveland Museum of Natural History, Oval Circle, Cleveland, OH, USA

Publication date: September 1, 2007


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