EMERGENCE OF `RETROPRO' STUDIES IN THE SURGICAL LITERATURE

Authors: Hall, JohnC.; Hall, JaneL.

Source: ANZ Journal of Surgery, Volume 78, Number 5, May 2008 , pp. 411-413(3)

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Abstract:

Background:

The surgical published work now contains several studies that involve retrospective evaluations of prospectively collected data. These types of studies - that are referred to as `RetroPro' studies - have the potential to be a valuable source of information about the care of surgical patients. The aim of this study was to evaluate the role of RetroPro studies in the surgical published work. Methods:

Original articles from 21 surgical journals were selected for study. Rejected from study were case reports, short communications, editorials, and surgical narratives (history, opinions and orations). Each original article was evaluated to determine the source of the study, the topic under evaluation, the sample size, the study design and the use of statistics. Results:

Retrospective studies accounted for 34% of the 1386 original articles. The other main components were single-group prospective studies (20%), non-clinical experimental studies (13%), RetroPro studies (10%), review articles (9%) and clinical trials (5%). Almost one-third of the RetroPro studies evaluated more than 1000 patients and 58% of them included some form of multivariable regression or an analysis of survival; that is, they attempted to model the outcome of surgical patients. Conclusion:

RetroPro studies are now an important source of information about the outcome of surgical patients. They should be recognized as a specific form of clinical investigation.

Keywords: biostatistics; clinical trial; evidence-based medicine; original article; surgery

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1445-2197.2008.04489.x

Publication date: 2008-05-01