A comparison of intubating conditions in children following induction of anaesthesia with propofol and suxamethonium or propofol and remifentanil
Authors: Morgan, J. M.1; Barker, I.2; Peacock, J. E.3; Eissa, A.2
Source: Anaesthesia, Volume 62, Number 2, February 2007 , pp. 135-139(5)
Publisher: Blackwell Publishing
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Abstract:
Summary Sixty ASA 1 and 2 children aged between 2 and 16 years who required tracheal intubation as part of anaesthesia for elective surgery were studied. We evaluated intubating conditions, haemodynamic responses and duration of apnoea following propofol 4 mg.kg−1 combined with either remifentanil 1.25 μg.kg−1 (group R), or suxamethonium 1 mg.kg−1 (group S). Tracheal intubation was graded as excellent, good or poor according to ease of laryngoscopy, vocal cord position, coughing, and jaw relaxation and limb movement. Thirty of group S and 28 of group R children were successfully intubated on the first attempt. Overall, intubation conditions were excellent or good in 26/30 (87%) patients in group S and 20/30 (67%) in group R (p < 0.05). Mean apnoea time was 190 s in group S, and 362 s in group R (p < 0.001). Heart rate increased in response to suxamethonium (p < 0.01) and both systolic and diastolic blood pressure decreased in the remifentanil group (p < 0.01).Document Type: Research article
DOI: 10.1111/j.1365-2044.2006.04903.x
Affiliations: 1: Registrar 2: Consultant, Department of Anaesthesia, Sheffield Children's Hospital, Western Bank, Sheffield S10 2TH, UK 3: Consultant, Department of Anaesthesia, Royal Hallamshire Hospital, Western Bank, Sheffield S10 2TH, UK
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