Authors: Kruptisky, E. M.1; Burakov, A. M.1; Tsoy, M. V.1; Egorova, V. Y.1; Slavina, T. Y.1; Grinenko, A. Y.1; Zvartau, E. E.1; Woody, G. E.
Source: Addiction, Volume 102, Number 7, July 2007 , pp. 1164-1165(2)
Publisher: Blackwell Publishing
Abstract:
Aim To describe a situation in which an opioid-dependent patient overcame naltrexone blockade. Design, case report, setting Addiction treatment center in St Petersburg, Russia. Participant Patient with naltrexone implant. Intervention Detoxification. Measurements Clinical observations. Conclusions It is possible, but very difficult, to overcome naltrexone blockade by using large doses of heroin.Keywords: Heroin addiction; naltrexone; opioid blockade; overdose; relapse
Document Type: Research article
DOI: 10.1111/j.1360-0443.2007.01817.x
Affiliations: 1: St Petersburg Regional Center for Research in Addiction and Psychopharmacology affiliated with Pavlov State Medical University, St Petersburg, Russia and
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