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Changing profiles of injecting drug users with AIDS in a Hispanic population

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Abstract:

ABSTRACT Aims 

To describe and assess the changing trends in socio-demographic, risk, clinical and immunological parameters in male intravenous drug users (IDU) with AIDS. Design, setting and participants 

Baseline description by year of entry of 610 male IDU with AIDS who entered into a cohort study in Bayamón, Puerto Rico, from 1992 to 2000. Study participants were evaluated at in-patient health-care facilities in the University Hospital Ramón Ruiz Arnau or in the ambulatory immunology clinic facilities. Findings 

The median age at which subjects entered the study and the proportion of patients with an educational level lower than a high school degree increased from 1992 to 2000. Upward trends were also observed in the practice of injecting non-prescription drugs during the last 12-month period, the practice of needle sharing and the use of a combination of heroin and cocaine (‘speedballs’). Higher proportions of subjects were also diagnosed with wasting syndrome and bacterial pneumonia. The median CD4 count recorded at entry decreased over the course of the study. Conclusions 

Puerto Rican male IDU diagnosed with AIDS are arriving at health-care facilities in the latest stages of the disease. Better and early interventions with different health care approaches need to be developed.

Keywords: AIDS; Puerto Rico; intravenous drug (ID) use; trends

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1360-0443.2004.00812.x

Affiliations: 1: Retrovirus Research Center, Internal Medicine Department, Universidad Central de Caribe, Puerto Rico 2: Department of Biostatistics, University of North Carolina at Chapel Hill, USA 3: Department of Microbiology and Immunology, Universidad Central de Caribe, Puerto Rico

Publication date: September 1, 2004

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