ISSN 1474-9718
Publisher: Wiley-Blackwell
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Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics) pp. 1-13(13) Authors: Uchiki, Tomoaki; Weikel, Karen A.; Jiao, Wangwang; Shang, Fu; Caceres, Andrea; Pawlak, Dorota; Handa, James T.; Brownlee, Michael; Nagaraj, Ram; Taylor, Allen
Wnt/β-catenin signaling is critical for dedifferentiation of aged epidermal cells <i>in vivo</i> and <i>in vitro</i> pp. 14-23(10) Authors: Zhang, Cuiping; Chen, Peng; Fei, Yang; Liu, Bo; Ma, Kui; Fu, Xiaobing; Zhao, Zhili; Sun, Tongzhu; Sheng, Zhiyong
The relationship between DNA methylation and telomere length in dyskeratosis congenita pp. 24-28(5) Authors: Gadalla, Shahinaz M.; Katki, Hormuzd A.; Shebl, Fatma M.; Giri, Neelam; Alter, Blanche P.; Savage, Sharon A.
Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages pp. 29-40(12) Authors: Jiang, Minghong; Xiang, Yang; Wang, Dongsheng; Gao, Jing; Liu, Dan; Liu, Yanxin; Liu, Shilian; Zheng, Dexian
Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency pp. 41-50(10) Authors: Menendez, Sergio; Camus, Suzanne; Herreria, Aida; Paramonov, Ida; Morera, Laura B.; Collado, Manuel; Pekarik, Vlad; Maceda, Iago; Edel, Michael; Consiglio, Antonella; Sanchez, Adriana; Li, Han; Serrano, Manuel; Belmonte, Juan C. I.
Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes pp. 51-62(12) Authors: Yoshiike, Yuji; Yamashita, Shunji; Mizoroki, Tatsuya; Maeda, Sumihiro; Murayama, Miyuki; Kimura, Tetsuya; Sahara, Naruhiko; Soeda, Yoshiyuki; Takashima, Akihiko
Alterations in phosphatidylethanolamine levels affect the generation of Aβ pp. 63-72(10) Authors: Nesic, Iva; Guix, Francesc X.; Vennekens, Krist'l; Michaki, Vasiliki; Van Veldhoven, Paul P.; Feiguin, Fabian; De Strooper, Bart; Dotti, Carlos G.; Wahle, Tina
Metabolic effects of intra-abdominal fat in GHRKO mice pp. 73-81(9) Authors: Masternak, Michal M.; Bartke, Andrzej; Wang, Feiya; Spong, Adam; Gesing, Adam; Fang, Yimin; Salmon, Adam B.; Hughes, Larry F.; Liberati, Teresa; Boparai, Ravneet; Kopchick, John J.; Westbrook, Reyhan
A new role for laminins as modulators of protein toxicity in <i>Caenorhabditis elegans</i> pp. 82-92(11) Authors: Jensen, Louise T.; Møller, Tine H.; Larsen, Simon A.; Jakobsen, Helle; Olsen, Anders
Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in <i>Drosophila</i> pp. 93-103(11) Authors: Wang, Ching-Tzu; Chen, Yi-Chun; Wang, Yi-Yun; Huang, Ming-Hao; Yen, Tzu-Li; Li, Hsun; Liang, Cyong-Jhih; Sang, Tzu-Kang; Ciou, Shih-Ci; Yuh, Chiou-Hwa; Wang, Chao-Yung; Brummel, Theodore J.; Wang, Horng-Dar
Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly pp. 104-110(7) Authors: Qian, Feng; Wang, Xiaomei; Zhang, Lin; Chen, Shu; Piecychna, Marta; Allore, Heather; Bockenstedt, Linda; Malawista, Stephen; Bucala, Richard; Shaw, Albert C.; Fikrig, Erol; Montgomery, Ruth R.
Physical exercise attenuates age-associated reduction in endothelium-reparative capacity of endothelial progenitor cells by increasing CXCR4/JAK-2 signaling in healthy men pp. 111-119(9) Authors: Xia, Wen-Hao; Li, Jing; Su, Chen; Yang, Zhen; Chen, Long; Wu, Fang; Zhang, Yuan-Yuan; Yu, Bing-Bo; Qiu, Yan-Xia; Wang, Shen-Ming; Tao, Jun
Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan pp. 120-127(8) Authors: Reis-Rodrigues, Pedro; Czerwieniec, Gregg; Peters, Theodore W.; Evani, Uday S.; Alavez, Silvestre; Gaman, Emily A.; Vantipalli, Maithili; Mooney, Sean D.; Gibson, Bradford W.; Lithgow, Gordon J.; Hughes, Robert E.
Aging-associated B7-DC<sup>+</sup> B cells enhance anti-tumor immunity via Th1 and Th17 induction pp. 128-138(11) Authors: Tomihara, Kei; Shin, Takako; Hurez, Vincent J.; Yagita, Hideo; Pardoll, Drew M.; Zhang, Bin; Curiel, Tyler J.; Shin, Tahiro
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart pp. 139-149(11) Authors: Vinciguerra, Manlio; Santini, Maria Paola; Martinez, Conception; Pazienza, Valerio; Claycomb, William C.; Giuliani, Alessandro; Rosenthal, Nadia
A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction pp. 150-161(12) Authors: Miller, Benjamin F.; Robinson, Matthew M; Bruss, Matthew D.; Hellerstein, Marc; Hamilton, Karyn L.
The p66<sup>Shc</sup> knocked out mice are short lived under natural condition pp. 162-168(7) Authors: Giorgio, Marco; Berry, Alessandra; Berniakovich, Ina; Poletaeva, Inga; Trinei, Mirella; Stendardo, Massimo; Hagopian, Kevork; Ramsey, Jon J.; Cortopassi, Gino; Migliaccio, Enrica; Nötzli, Sarah; Amrein, Irmgard; Lipp, Hans P.; Cirulli, Francesca; Pelicci, Pier G.
Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth pp. 169-177(9) Authors: Griffith, Ann V.; Fallahi, Mohammad; Venables, Thomas; Petrie, Howard T.
Age-related variation in immunity in a wild mammal population pp. 178-180(3) Authors: Nussey, Daniel H.; Watt, Kathryn; Pilkington, Jill G.; Zamoyska, Rose; McNeilly, Tom N.