A review of a life of unusual achievement, prepared by Patrick A Wayman. I present here a review of the career of one of the 20th century’s most important astronomers, who succeeded in working at the forefront of astrophysics. It is also a story of persistence against the odds, whether they were low expectations of women or academic infighting. The story has resonance for those beginning careers today, in a very different academic environment. It also provides an overview of the development of the astrophysics of stellar composition over a long and fruitful career.