Issues of the nature and task of theology remain important to the science-theology dialogue. This paper lays out a framework for understanding the nature of theology in relation to the other sciences. In particular, I argue that the primary question remains one of autonomy and reduction. If theology is a genuine academic discipline, then it should be an autonomous field with its own subject matter and norms. Wolfhart Pannenberg argues that theology is the science of God, but I suggest that theology be more broadly understood as the science of meaning. If we recognize this, the modes of interaction between theology and the other sciences becomes clearer.