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Case–control studies with complex sampling

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The use of complex sampling designs in population-based case–control studies is becoming more common, particularly for sampling the control population. This is prompted by all the usual cost and logistical benefits that are conferred by multistage sampling. Complex sampling has often been ignored in analysis but, with the advent of packages like SUDAAN, survey-weighted analyses that take account of the sample design can be carried out routinely. This paper explores this approach and more efficient alternatives, which can also be implemented by using readily available software.
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Keywords: Case–control studies; Correlated data; Intracluster correlation; Logistic regression; Multistage sampling

Document Type: Research Article

Affiliations: University of Auckland, New Zealand

Publication date: 2001-01-01

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