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Still-births among the offspring of male radiation workers at the Sellafield nuclear reprocessing plant: detailed results and statistical aspects

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This study investigates whether there was evidence of increasing risk of still-birth with increasing paternal exposure to ionizing radiation received during employment at the Sellafield nuclear installation before the child was conceived. A significant positive association is found between the total paternal preconceptional exposure to external ionizing radiation and the risk of still-birth (after adjustment for year of birth, social class, birth order and paternal age, odds ratio at 100┬ámSv 1.24 (95% confidence interval 1.04–1.45)). A summary of the principal scientific findings of this study has been published in the Lancet. This paper describes in detail the statistical methods that were used in the investigation and presents the results in full.
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Keywords: Cohort; Logistic regression; Occupational exposure; Radiation effects; Still-birth; Variance components models

Document Type: Research Article

Affiliations: University of Newcastle, UK

Publication date: 2002-10-01

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