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Survival and neurodevelopmental outcome of ELBW children at 5 years of age

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Aim:  To examine survival and outcome of extremely low‐birth‐weight (ELBW) children (birth weight < 1000 g) in two 5‐year periods, 10 years apart.

Methods:  In a retrospective population‐based study, information on all ELBW children born in Iceland in 1991–1995 and in 2001–2005 was obtained from the National Birth Registry, hospital charts and medical records. The two periods were compared.

Results:  In 1991–1995, 102 of 22.261 newborn children (0.5%) were extremely low birth weight compared with 70 of 20.923 newborns (0.33%) in 2001–2005 (p = 0.04). At 5 years of age, 52% (35/67) of live‐born children born in 1991–1995 were alive compared with 63% (31/49) of children born in 2001 – 2005 (p = 0.2). Six ELBW children (17%) born 1991–1995 were diagnosed with disabilities at 5 years of age, three with major neurodevelopmental disabilities compared with six (19%) born 2001–2005, thereof one with severe neurodevelopmental disabilities (p = 0.57).

Conclusion:  The incidence of childhood disabilities in ELBW children in Iceland remains stable despite an increase in survival rate. The severity of neurodevelopmental disabilities has decreased.

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1651-2227.2012.02645.x

Affiliations: 1: .Faculty of Medicine, The University of Iceland, Saemundargata, Reykjavik, Iceland 2: .The State Diagnostic and Counselling Centre, Kopavogur, Iceland

Publication date: July 1, 2012



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