Cardiac biomarkers in neonatal hypoxic ischaemia

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Following a perinatal hypoxic–ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin‐T, troponin‐I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long‐term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow‐up studies are warranted to ensure optimal cardiac function in adulthood.

Conclusion:  Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic‐ischaemia.

Document Type: Research Article


Publication date: April 1, 2012

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