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Moderately elevated body mass index is associated with metabolic variables and cardiovascular risk factors in Swedish children

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Abstract Aim: 

To evaluate associations between anthropometrics and metabolic variables as well as cardiovascular risk factors among children. Methods: 

Subjects were recruited from a cohort of 274 healthy children in Umeå, Sweden. Anthropometric measures, blood pressure and venous blood samples were collected at age 10 years and simultaneously from parents. Results: 

Altogether 144 children (53%), 142 mothers and 123 fathers participated. The prevalence of overweight and obesity among the children was 18 and 2%, respectively. Overweight children (above age- and sex-specific cut offs corresponding adult BMI ≥ 25 kg/m2), compared to normal weight children, had significantly higher BMI already during infancy and higher S-insulin and Homeostatic Model Assessment (HOMA) index at 10 years. The children’s BMI was positively associated with waist (boys’ r = 0.67, girls’ r = 0.81), hip (r = 0.68), waist/hip ratio (girls’ r = 0.37), waist/height ratio (boys’ r = 0.59, girls’ r = 0.80), sagittal abdominal diameter (r = 0.75), S-insulin (r = 0.45), HOMA index (r = 0.49), systolic blood pressure (r = 0.24), mothers’ BMI (girls’ r = 0.42) and mothers’ waist (girls’ r = 0.42). Conclusion: 

Children at 10 years of age with moderately elevated BMI had higher levels of some metabolic variables and cardiovascular risk factors than did normal weight children, and there was a correlation between BMI and some metabolic variables as well as cardiovascular risk factors.

Keywords: BMI; Children; Metabolic syndrome; Obesity; Overweight

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1651-2227.2010.01969.x

Affiliations: 1: Department of Food and Nutrition, Umeå University, Umeå, Sweden 2: Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden

Publication date: January 1, 2011

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