Neonatal renal vein thrombosis and prothrombotic risk
A case of extensive deep venous thrombosis in a four a day old infant was presented. Unusually this patient was shown to be heterozygous for three thrombophilia genes; Factor V Leiden, prothrombin and antithrombin gene mutations, the latter being novel. Conclusion:
There are no randomized controlled trials to guide management in deep venous thrombosis in the newborn but knowledge of the prothrombotic risk factors may help direct treatment.
Document Type: Research Article
Affiliations: 1: Neonatal Unit, Christchurch Women's Hospital, Christchurch, New Zealand 2: Department of Haematology, Canterbury District Health Board, Christchurch, New Zealand 3: Canterbury Health Laboratories, Christchurch, New Zealand 4: Department of Paediatrics, Christchurch School of Medicine, University of Otago, Christchurch, New Zealand
Publication date: July 1, 2010