Phenotype of acute respiratory syncytial virus induced lower respiratory tract illness in infancy and subsequent morbidity
Source: Acta Pædiatrica, Volume 96, Number 2, February 2007 , pp. 307-309(3)
Abstract:The objective of this study was to investigate the association hypothesis that outcome following respiratory syncytial virus (RSV) induced bronchiolitis (RSVB) and RSV induced wheeze (RSVW) are different. At 3 years respiratory symptoms were more common in those with RSV infection than the control group but there was no increase in allergic sensitisation (11%vs 10%). Those with RSVW were more likely to have evidence of allergic sensitisation when compared with RSVB subjects (22%vs 7%), and have increased symptoms and increased use of inhaled steroids. Conclusion: The data argue that RSV infection during infancy does not induce allergic asthma and that host factors rather than the virus determine long-term outcomes.
Document Type: Short communication
Publication date: 2007-02-01