Skip to main content

Hormonal status of short children born small for gestational age

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

The present study was undertaken to evaluate the hormonal status in a subgroup of prepubertal children born small for gestational age (SGA) who lacked postnatal catch‐up growth. In this subgroup, a reduced rate of growth hormone (GH) secretion was found, compared with reference groups of healthy children born appropriate for gestational age, of either normal or short stature at the time of investigation. In addition, an abnormal pattern of GH secretion was observed in short children born SGA, which was most pronounced in the younger children, and involved an increased frequency of GH peaks of low amplitude, combined with increased baseline secretion. Levels of insulin‐like growth factor I (IGF‐I) and IGF‐binding protein‐3 were also reduced in short children bora SGA, compared with the reference groups. These findings may explain, in part, the lack of postnatal catch‐up growth in short children born SGA. □ Small for gestational age, growth hormone secretion, growth hormone‐binding protein, insulin‐like growth factor I, insulin‐like growth factor‐binding protein‐3

Document Type: Review Article

DOI: http://dx.doi.org/10.1111/j.1651-2227.1997.tb18412.x

Affiliations: International Pediatric Growth Research Centre, Department of Pediatrics, University of Göteborg, Göteborg, Sweden

Publication date: November 1, 1997

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more