Variation of bone age progression in healthy children

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Bone age assessments were related to auxological variables in 407 Italian boys, between 7 and 12 years of age, in order to elucidate the factors that affect the rate of skeletal maturation and to examine the possibility of using measures of skeletal maturation to evaluate individual patients. Using the radius—ulna—short bones (RUS) method of assessment, bone age velocity was greater in the Italian boys than for the UK reference standards, although there was considerable interindividual dispersion around the mean. Bone age velocity and height velocity were poorly correlated, and there was little correlation between skeletal and pubertal maturation. There was a slight positive correlation between bone age velocity and height SDS and between bone age velocity and body mass index. Bone age estimations using RUS were greater than those obtained using the carpus. In conclusion, the marked interindividual deviation in measured bone ages makes it difficult to relate data on an individual basis to other measures of growth and maturation. □ Bone age, bone age velocity, skeletal maturation, height, height velocity, body mass index

Document Type: Short Communication


Affiliations: 1: Centra di Auxologia, Università di Milano, Milan, Italy 2: Divisione di Endocrinologia, Università di Milano, Milan, Italy 3: Università di Torino, Torino, and Istituto di Statistica Medicae Biometria, Università di Milano, Milan, Italy

Publication date: November 1, 1997

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