Skip to main content

Gene regulation in the formation of the central nervous system

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

In this review recent advances in our understanding of the genetic control of central nervous system development will be discussed. Stem and/or progenitor cells in the neuroepithelium of the neural tube differentiate into neurons and glial cells in the brain and spinal cord. There is an emerging picture of how key regulatory genes act to control various steps in this differentiation pathway, including organization along the anterio‐posterior and dorso‐ventral body axes. Examples from our own research on nestin and Notch genes will also be presented. It is our hope that information about the biology of these genes may shed light on the nature of the central nervous system stem cell and its developmental decisions.

Document Type: Original Article

DOI: https://doi.org/10.1111/j.1651-2227.1997.tb18337.x

Affiliations: Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden

Publication date: 1997-07-01

  • Access Key
  • Free ContentFree content
  • Partial Free ContentPartial Free content
  • New ContentNew content
  • Open Access ContentOpen access content
  • Partial Open Access ContentPartial Open access content
  • Subscribed ContentSubscribed content
  • Partial Subscribed ContentPartial Subscribed content
  • Free Trial ContentFree trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more