Mild Palladium‐Catalyzed Oxidative Direct
Palladium‐catalyzed cross‐dehydrogenative coupling between anilides and aromatic aldehydes was achieved under aqueous conditions. A wide variety of the desired benzophenone derivatives was isolated in good to excellent yield. The reaction rate acceleration effect of acid and detergent has been demonstrated. Mechanistic insight has been obtained from quantum chemical calculations.
Document Type: Communications
Affiliations: 1: MTA-ELTE “Lendület” Catalysis and Organic Synthesis Research Group, Institute of Chemistry, Eötvös University, Pázmány Péter stny 1/a, H-1117 Budapest, Hungary 2: Institute of Chemistry, Eötvös University, Pázmány Péter stny 1/a, H-1117 Budapest, Hungary 3: Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Laboratory of Theoretical Chemistry, Pusztaszeri út 59-67, H-1025 Budapest, Hungary
Publication date: 2013-03-11