Room Temperature Palladium‐Catalyzed Decarboxylative Acyl/Aroylation using [Fe(III)(EDTA)(η
The purple‐coloured iron peroxo complex [Fe(III)EDTA(η2‐O2)]3− as a novel reagent system for Pd‐catalyzed decarboxylative ortho‐acylation of acetanilides with α‐oxocarboxylic acids at room temperature in aqueous media has been realized. This reaction provides an effective access to ortho‐acylacetanilides under mild conditions.
Document Type: Communications
Affiliations: Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, ChattarManzil Palace, Lucknow – 226-001, India, extn. 4268; (+91)-522-351-638, Fax: (+91)-522-2212411-18
Publication date: 2013-03-11