Iron‐Catalyzed Tandem One‐Pot Addition and Cyclization of the Blaise Reaction Intermediate and Nitroolefins: Synthesis of Substituted NH‐Pyrroles from Nitriles
The iron‐catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH‐pyrroles in a tandem one‐pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH‐pyrroles in good yields.
Document Type: Research Article
Affiliations: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, People's Republic of China
Publication date: January 14, 2013