Iron‐Catalyzed CC Bond Cleavage and CN Bond Formation
A novel approach for CN bond formation was developed by iron‐catalyzed CC bond cleavage. Anilines and sulfonamides reacted smoothly with 2‐substituted 1,3‐diphenylpropane‐1,3‐diones to afford N‐alkylation products, in which the 1,3‐dicarbonyl group acts as a leaving group in the presence of an iron catalyst. The reversible CC bond cleavage plays a driving force to give the thermodynamically stable products. The method is complementary to the previous methods for CN bond formation.
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Document Type: Research Article
Affiliations: Department of Chemistry, Renmin University of China, Beijing 100872, People's Republic of China, Fax: (+86) 10-6251-6444
Publication date: 2013-01-14