Skip to main content

Highly Stereoselective Syntheses of All 1,2,3‐

Buy Article:

$43.00 plus tax (Refund Policy)

Abstract

Iridium‐catalyzed asymmetric hydrogenations of chiral alkenes were used to access four pivotal α,ω‐functionalized chirons, that contain widely occurring stereochemical 1,2,3‐Me,OH,Me motifs. A chiral analogue of Crabtree’s catalyst was used in key hydrogenation steps to form these motifs with high stereochemical purities. An application of one of these chirons is illustrated here with a synthesis of (−)‐invictolide.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Document Type: Research Article

Affiliations: Department of Chemistry, Texas A& M University, Box 30012, College Station, TX 77842-3012, USA, phone: (+1)-979-845-4345, Fax: (+1)-979-845-8839

Publication date: 2013-01-14

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more